A genomic island defines subspecies - specific virulence features of the host adapted 1 pathogen
نویسندگان
چکیده
A genomic island defines subspecies-specific virulence features of the host adapted 1 pathogen Campylobacter fetus subsp. venerealis. 2 3 Gregor Gorkiewicz, 1, 2* Sabine Kienesberger, 1, 2 Caroline Schober, 1 Sylvia R. Scheicher, 1 4 Christian Gülly, 3 Rudolf Zechner, 1 and Ellen L. Zechner 1 5 6 Institute for Molecular Biosciences, Karl-Franzens-University of Graz, Humboldtstrasse 50/I, 7 8010 Graz, Austria. 1 Institute of Pathology, Medical University of Graz, Auenbruggerplatz 25, 8 8036 Graz, Austria. 2 Center for Medical Research, Medical University of Graz, Stiftingtalstrasse 9 24, 8010 Graz, Austria. 3 10 11 12 13 14 Running title: Genomic island of Campylobacter fetus 15 16 17
منابع مشابه
A genomic island defines subspecies-specific virulence features of the host-adapted pathogen Campylobacter fetus subsp. venerealis.
The pathogen Campylobacter fetus comprises two subspecies, C. fetus subsp. fetus and C. fetus subsp. venerealis. Although these taxa are highly related on the genome level, they are adapted to distinct hosts and tissues. C. fetus subsp. fetus infects a diversity of hosts, including humans, and colonizes the gastrointestinal tract. In contrast, C. fetus subsp. venerealis is largely restricted to...
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متن کاملComparative Genome Analysis of Campylobacter fetus Subspecies Revealed Horizontally Acquired Genetic Elements Important for Virulence and Niche Specificity
Campylobacter fetus are important animal and human pathogens and the two major subspecies differ strikingly in pathogenicity. C. fetus subsp. venerealis is highly niche-adapted, mainly infecting the genital tract of cattle. C. fetus subsp. fetus has a wider host-range, colonizing the genital- and intestinal-tract of animals and humans. We report the complete genomic sequence of C. fetus subsp. ...
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